New york: Major US stock indexes closed lower on Wednesday, dragged down by losses in the technology sector. According to Qatar News Agency, the S and P 500 fell 14.34 points, or 0.19 percent, to close at 7,485.02. The Nasdaq Composite lost 169.56 points, or 0.65 percent, to reach 26,044.16. The Dow Jones Industrial Average slipped 3.62 points, or 0.01 percent, to close at 52,315.58. The technology sector experienced notable declines, contributing significantly to the overall market downturn. Investors appeared cautious amid uncertainties surrounding the sector's performance. The drop in these key indexes signals a broader market sentiment influenced by the tech industry's setbacks.